https://youtu.be/pPE8WBJLQQE?si=-BSqkpmHzgZa34JL 1. Definition and Nature of Andropause ("Male Menopause") Gradual Hormonal Decline: Andropause (also called late-onset hypogonadism or Irritable Male Syndrome) represents a slow, decades-long decline in testosterone and other androgenic hormones. Age Trajectory: Total testosterone levels typically peak in the late teens to mid-20s and decline at roughly 1% to 2% per year starting between ages 30 and 40. By age 70, testosterone levels may drop 30% to 50% below peak levels. Key Differences from Female Menopause: Unlike female menopause—which is abrupt, universal, and marked by the total cessation of ovulation and menstruation—andropause is gradual, highly variable between individuals, and lacks a single universal biological threshold. Prevalence: Declining testosterone and low testosterone symptoms affect approximately 38.7% to 40% of men over age 45.
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